THROMBOSIS IN INFLAMMATORY BOWEL DISEASE:MECHANISMS AND RISK FACTORS

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Vol. 87 No. 5 (2009): Issue May 2009

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Leila Mouelhi
Haïfa Mekki
Radhouane Debbeche
Mohamed Salem
Taoufik Najjar

Abstract

Background : Thromboembolic manifestations are frequent in patients with inflammatory bowel disease.
Aims: To explaim the mechanisms of thromboembolic manifestations in inflammatory bowel disease.
Methods: Literature review.
Results: Risk factors of thrombosis in inflammatory bowel disease are acquired or genetic. The most important factors are thrombocytosis, increased of activation of platelets and hyperhomocysteinemia. Other factors such factor V leiden, antithrombin III and antiphospholipid antibodies are observed in inflammatory bowel disease patients but not always correlated with thromboembolic manifestations.
Conclusion: The mechanisms of thrombosis in inflammatory bowel disease are complex are intricate.

Keywords:

Thrombosis, Inflammatory bowel disease

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