Leila Mnif
Ali Amouri
Mohamed A Masmoudi
Amin Mezghanni
Naourez Gouiaa
Tahia Boudawara
Nabil Tahri


Background : Colonic lipomas are benign adipose tumors which are usually submucosal. Small lesions are asymptomatic and may be detected incidentally. Large lipomas can cause symptoms.
Aim : We report a case of symptomatic giant colonic lipoma
Observation :A 67-year old woman was admitted to hospital with persistent abdominal pain, for which a barium enema showed a large polypoid mass occluding the lumen of the transverse colon. Colonoscopy revealed a tumor narrowing the bowel lumen of about 5 cm in diameter with a sessile appearance and ulcerated overlying mucosa. The possibility of colonic malignancy could not be precluded and an operative resection was performed. Pathological examination revealed a colonic lipoma. Twelve months after the surgery, the patient was free of symptoms.
Conclusion: Awareness of the possibility of colonic lipomas is important for clinicians in terms of evaluation of therapeutic regimen.


Colonic, lipoma, malignancy, diagnosis, therapy



  1. Pfeil SA, Weaver MG, Abdul-Karim FW, Yang P. Colonic lipomas: outcome of endoscopic removal. Gastrointest Endosc 1990; 36:435-8.
  2. El-Khalil T, Mourad FH, Utham S. Sigmoid lipoma mimicking carcinoma: case report with review of diagnosis and management. Gastrointestinal Endoscopy 2000; 51:495-6.
  3. Kim CY, Bandres D, Tio TL, Benjamin SB, Al-Kawas FH. Endoscopic removal of large colonic lipomas. Gastrointestinal Endoscopy 2002; 55:929- 31.
  4. Jiang L, Jiang LS, Li FY, Ye H, Li N, Cheng NS, Zhou Y. Giant submucosal lipoma located in the descending colon: a case report and review of the literature. World J Gastroenterol 2007; 13:5664-7.
  5. Katsinelos P, Chatzimavroudis G, Zavos C, et al. Cecal lipoma with pseudomalignant features: A case report and review of the literature. Wold J Gastroenterol 2007; 13: 2510-13.
  6. Loludice TA, Lang JA. Submucous lipoma simulating carcinoma of the colon. South Med J 1980; 73: 521-3.
  7. Lera JM, Gomez-Portilla A, Fakih A, Vicente F, Zornoza G. Submucosal lipomas of the colon. Rev Med Univ Navarra 1982; 26: 185-7.
  8. Snover DC. Atypical lipomas of the colon. Report of two cases with pseudomalignant features. Dis Colon Rectum 1984; 27:485-8.
  9. McGrew W, Dunn GD. Colonic lipomas: clinical significance and management. South Med J 1985; 78:877-9.
  10. Taylor BA, Wolff BG. Colonic lipomas. Report of two unusual cases and review of the Mayo Clinic experience, 1976-1985. Dis Colon Rectum 1987; 30:888-893.
  11. Ibrazullah M, Aggarwal R, Choudhuri G, Tandon P, Kapoor VK. Colonic lipoma, masquerading as malignant tumor. Indian J Cancer 1992; 29:4-6.
  12. Chase MP, Yarze JC. “Giant” colon lipoma-To attempt endoscopic resection or not? Am J Gastroenterol 2000; 95:2143-4.
  13. Tamura S, Yokoyama Y, Morita T, Tadokoro T, Higashidani Y, Onishi S. « Giant » colon lipoma: what kind of necessary for the indication of endoscopic resection? Am J Gastroenterol 2001; 96:1944-6.
  14. Stone C, Weber HC. Endoscopic removal of colonic lipomas. Am J Gastroenterol 2001; 96:1295-6.
  15. Rogers SO Jr, Lee MC, Ashley SW. Giant colonic lipoma as lead point for intermittent colo-colonic intussusception. Surgery 2002; 131:687-8.
  16. Caterino S, Tiziano G, Mercantini P, Ziparo V. Rectorrhagia caused by lipoma of the hepatic flexure of the colon. A case report and review of the literature. G Chir 2002; 23: 205-8.
  17. Ãœstünsoy E, Türeyen A, Topçu I, Basim H. Intestinal obstruction due to a giant lipoma of the ascending colon: a case report. Turk J Gastroenterol 2003; 14:280-1.
  18. Meghoo CA, Cook PR, McDonough CA, Bowser LK, Waddell BE. Large colonic lipoma with mucosal ulceration mimicking carcinoma. Gastrointest Endosc 2003; 58:468-70.
  19. Ghidirim G, Mishin I, Gutsu E, Gagauz I, Danch A, Russu S. Giant submucasal lipoma of the cecum: report of a case and review of literature. Rom J Gastroenterol 2005; 14:393-6.
  20. Huh KC, Lee TH, Kim SM, et al. Intussuscepted sigmoid colonic lipoma mimicking carcinoma. Dig Dis Sci 2006; 51:791-5.
  21. Amer NM, Johnston D, Gutmann J. Image of the month-Quiz Case. Arch Surg 2006; 141 :833-4.
  22. Koktener A, Erden A. Usefulness of virtual colonoscopy in the diagnosis of symptomatic large colonic lipomas. Australasian Radiology 2007; 51: B144-6.
  23. Atila K, Terzi C, Obuz F, Yilmaz T, Füzün M. Symptomatic intestinal lipomas requiring surgical interventions secondary to ileal intussusception and colonic obstruction: report of two cases. Turkish journal of trauma &emergency surgery 2007; 13:227-231.
  24. Wild D, Fiore J, Guelrud M. Successful endoscopic resection of a giant colonic lipoma causing intussusception. Gastrointest Endosc. 2008; article in press.
  25. Chung YF, Ho YH, Nyam DC, Leong AF, Seow-choen F. Management of colonic lipomas. Aust N Z J Surg 1998; 68: 133-5.
  26. Abou-Nukta F, Gutweiler J, khaw J, Yavorek G. Giant lipoma causing a colo-colonic intussusception. Am Surg 2006; 72:83-4.