Symptoms and natural history of hospital chronic obstructive pulmonary disease

##plugins.themes.academic_pro.article.main##

B. Ourari-Dhahri
H. Zaibi
J. Ben Amar
L. EL Gharbi
M. A Baccar
S. AzzabI
H. Aouina
H. Bouacha

Abstract

Background: Since few years, the data describing the chronic obstructive pulmonary disease (COPD) have changed and new concepts have emerged.
aim: To study the clinical characteristics and outcome of patients with COPD in a Tunisian population.
methods : It is a retrospective study including 150 patients with COPD admitted at the pulmonary department of Charles Nicolle Hospital in Tunis, during a period of ten years.
results : Data from 150 patients hospitalized at the pulmonary department of Charles Nicolle Hospital in Tunis, were analyzed. They were 126 men and 24 women with a mean age of 67 years. Tobacco was the predominant risk factor. Eighty-two (55%) patients were classified GOLD stage IV at diagnosis. The number of exacerbation varied from 1 to 7 with an average higher in patients classified as stage IV (p = 0.007).
Conclusion : The COPD is pathology of smoking men. Comorbidities and exacerbations prevalence increase according the disease severity. In fact, better knowledge of exacerbations etiologies allows considering better measurement of prevention.

Keywords:

COPD, exacerbations

##plugins.themes.academic_pro.article.details##

References

  1. Chaulet P. After health sector reform, whither lung health. International Journal of Tuberculosis Lung Disease, 1998; 2: 349- 359.
  2. Colley JRT, Reid DD. Urban and social origins of childhood bronchitis in England and Wales. British Medical Journal, 1970; 2: 213-217.
  3. Prescott E, Lange P, Vestbo J. Socioeconomic status, lung function and admission to hospital for COPD : results from the Copenhagen City Heart Study. European Respiratory Journal, 1999; 13: 1014-1019.
  4. Ait-Khaled N, Chaulet P, Enarsson D, Slama K. Epidemiology and management of stable chronic obstructive pulmonary disease in Africa. In: Similowski Derenne P. Clinical management of clinical obstructive pulmonary disease. New York, Marcel Dekker, 2002; 1007-1030.
  5. Wilson D, Adam R, Appletons S, Ruffin R. Difficulties identifying and targeting COPD and population-attributable risk of smoking for COPD: a population study, Chest, 2005; 28: 2035- 42.
  6. Murray CJ, Lopez AD. Evidence-based health policy-lessons from the Global Burden of Disease. Study Science, 1996; 274:740-3.
  7. Pandey MR. Domestic smoke pollution and chronic bronchitis in a rural community of Hill Region of Nepal. Thorax, 1984; 39: 337-339.
  8. Behera D, Jindal SK. Respiratory symptoms in Indian women using domestic cooking fuels. Chest, 1991; 100: 385-388.
  9. Wilson D, Adam R, Appletons S, Ruffin R. Difficulties identifying and targeting COPD and population-attributable risk of smoking for COPD: a population study. Chest, 2005; 28: 2035- 42.
  10. El Meziane A et al. Prévalence de la bronchite chronique en milieu industriel au Maroc. 13e Congrès médical magrhébin, Casablanca, 13-14 mai 1994.
  11. Yach D et al. A respiratory epidemiological survey of grain mill workers in Cape Town, South Africa. American Journal of Respiratory Critical Care Medicine, 1985, 131: 505-510.
  12. Wissam M, Chatila BM, Thomashow, Minai OA, Gerard JC, Barry J. Make. Comorbidities in Chronic Obstructive Pulmonary Disease.Proc Am Thorac Soc, 2008; 5: 549-555.
  13. K. Faure. Comment évaluer, orienter et suivre un patient ayant une pneumonie aiguë communautaire ? Une exacerbation de broncho-pneumopathie chronique obstructive? Évaluation des facteurs de risque d'acquisition, d'évolution compliquée et/ou de mortalité, des signes de gravité. Choix du lieu de la prise en charge et orientation du suivi. Med Mal Infect, 2006; 36: 734- 783.
  14. Seemungal TA, Donaldson GC, Bhowmik A, Jeffries DJ, Wedzicha JA. Time course and recovery of exacerbations in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 2000; 161: 1608-1613
  15. Iglesia MF, Pellicer vazquez C, Ramos polledo V, Nicolas miguel R, Pita fernandez S, Martinez F. Chronic obstructive pulmonary disease and the seasons of the year. Arch Bronconeumol, 2000; 36: 84-9.
  16. Connors AF, Dawson NV, Thomas C, et al. Outcomes following acute exacerbation of severe chronic obstructive lung disease. Am J Respir Crit Care Med, 1996; 154: 959-967.
  17. Sethi S, Murphy TF. Bacterial infection in chronic obstructive pulmonary disease in 2000: a state-of-the-art review. Clin Microbiol Rev, 2001; 14: 336-63.
  18. Bradley SQ, Wen QG and Sin DD. Contemporary Management of Acute Exacerbations of COPD: A Systematic Review and Metaanalysis. Chest, 2008; 133: 756-766.
  19. Mathers CD, Loncar D. Updated projections of global mortality and burden of disease, 2002-2030: data sources, methods and results. Evidence and information for policy, World Health Organization, October 2005.
  20. Bumgarner JR, Speizer FE. Chronic obstructive pulmonary disease. In: Jamison DT et al. Disease control priorities in developing countries. New York, Oxford University Press, 1993: 595-608.
  21. Ait-Khaled N, Enarson D, Bousquet J. Les maladies respiratoires chroniques dans les pays en développement : charge de morbidité et stratégies de prévention et de prise en charge. Bulletin of the World Health Organization, 2001; 79: 971-979.