Diffuse oesophageal spasms: results of a retrospective manometric study

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Published Jan 29, 2015
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Vol. 92 No. 7 (2014): Issue Jul 2014

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Meriem Serghini
Sabeh Ben Kahla
Sami Karoui
Lamia Kallel
Samira Matri
Nadia Ben Mustapha
Monia Fekih
Jalel Boubaker
Azza Filali

Abstract

Background: Diffuse esophageal spasms is a primary motor disrder of the esophagus of unknown etiology characterized by intermettent peristalsis. This is rare condition which represents 3-5% if primary disorders of the esophagus. Diagnosis and treatment of this entity are difficult.

Aims: To evaluate the frequency and the clinical and the manometric features of diffuse esophageal spasms. Methods: We conducted a retrospective study related to esophageal manometry performed between January 2000 and December 2011 regardless of the indication. Patients with meeting criteria for diffuse esophageal spasms (> 20 % simultaneous waves with greater than 30 mmHg pressure in the esophagus) were included.

Results: Out of 1188 patients, 13 (1,09 %) met the manometric criteria for diffuse esophageal spasms. It was 8 women and 5 men with a median age of 57 years. Dysphagia was the most relevant symptom and chest pain was only noted in 1 patient. The frequency of simultaneous waves was between 20 and 80 %. The pressure of the lower esophageal sphincter was normal in most cases.

Conclusion: In this Tunisian manometric study, the diffuse esophageal spasms is rare. Dysphagia was the most relevant symptom and the pressure of the lower esophageal sphincter was normal in most cases.

Keywords:

Esophageal motility disorders, Diffuse oesophageal spasms, oesophageal manometry

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