Role of depression in blood pressure control. A cross-sectional multicentric study

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Published Feb 11, 2024
https://doi.org/10.62438/tunismed.v102i1.4723
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Vol. 102 No. 1 (2024): Tunis med jan 2024

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Yosra Raddaoui
Hospital of Main Military Training of Tunis, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia
Ahmed Ben Amara
Regional hospital of Ben Arous, University of Tunis El Manar , Faculty of Medicine of Tunis. Tunisia
https://orcid.org/0000-0001-5346-6793
Aymen Noamen
Hospital of Main Military Training of Tunis, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia
https://orcid.org/0000-0002-6269-6440
Saoussen Antit
Hospital of Internal Security Forces La Marsa, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia
https://orcid.org/0000-0001-5157-9989
Youssef Hajri
Hospital of Internal Security Forces La Marsa, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia
Jamila Habli
Regional hospital of Ben Arous, Tunisia
Hassen Ibn Hadj Amor
Taher Sfar hospital -Mahdia, Tunisia
Youssef Ben Youssef
Taher Sfar hospital -Mahdia, Faculty of medicine of Tunis - Tunisia
Lilia Zakhama
Hospital of Internal Security Forces La Marsa, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia
https://orcid.org/0000-0001-6026-8592
Wafa Fehri
Hospital of Main Military Training of Tunis, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia
https://orcid.org/0000-0003-0312-8184

Abstract

Research Problem:  Hypertension is a multifactorial disease that affects approximately one third of the Tunisian adult population. It is a major risk factor for stroke and cardiovascular disease. Environmental and psychosocial factors play an important role in hypertension onset and control. The prevalence of depression among hypertensive patients is 26, 8% and its presence is associated with increased risk of cardiovascular-related morbi-mortality.


Our study aims to evaluate the role of depression in blood pressure control among ambulatory hypertensive patients.


Investigative process: This study is a cross-sectional, multicentric and descriptive study. We intend to include three hundred and two patients. A 24-hour ambulatory blood pressure monitor will be used to evaluate blood pressure control. Depression will be assessed by the 9-item-Patient Health Questionnaire (PHQ-9) in Tunisian dialect. Clinical, socio-environmental, psychosocial and therapeutic and prognosis data will be collected from medical records. Patients will be classified into two groups: Controlled versus non-controlled hypertension. PHQ-9 scores will be then compared between the two cohorts.


Research Plan: Ethical considerations will be undertaken and respected. All patients should express an informed oral consent before enrollment. This trial will run for three months from the 15th August 2022.


Trial registration: NCT05516173

Keywords:

hypertension, depression, Patient Health Questionnaire, Blood Pressure Monitoring, Ambulatory, Tunisia

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