Impact of COVID-19 on child tuberculosis hospitalization

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Published Jun 28, 2024
https://doi.org/10.62438/tunismed.v102i7.4923
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Vol. 102 No. 7 (2024): Tunis Med jul 2024

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Sanae Zaidi
Laboratory of Clinical Immunology, Inflammation and Allergy (LICIA), Casablanca Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco
Abderrahmane Errami
Laboratory of Clinical Immunology, Inflammation and Allergy (LICIA), Casablanca Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco
Ikbal Belkhou
Laboratory of Clinical Immunology, Inflammation and Allergy (LICIA), Casablanca Faculty of Medicine and Pharmacy, Hassan II University, Pediatric Gastroenterology Unit, CHU Ibn Rochd, Faculty of Medicine, A.Harouchi Hospital CHU Ibn Rochd Casablanca, Morocco.
Meryem Elkhaldi
Children Infectious and Clinical Immunology department Casablanca Children’s Hospital, Ibn Rochd University Hospital, Morocco
Fatima Ailal
Laboratory of Clinical Immunology, Inflammation and Allergy (LICIA), Casablanca Faculty of Medicine and Pharmacy, Hassan II University, Children Infectious and Clinical Immunology department Casablanca Children’s Hospital, Ibn Rochd University Hospital.Casablanca, Morocco.
Ibtihal Benhsaien
Laboratory of Clinical Immunology, Inflammation and Allergy (LICIA), Casablanca Faculty of Medicine and Pharmacy, Hassan II University, Children Infectious and Clinical Immunology department Casablanca Children’s Hospital, Ibn Rochd University Hospital.Casablanca, Morocco.
Fatima Adnane
Laboratory of Clinical Immunology, Inflammation and Allergy (LICIA), Casablanca Faculty of Medicine and Pharmacy, Hassan II University, Children Infectious and Clinical Immunology department Casablanca Children’s Hospital, Ibn Rochd University Hospital.Casablanca, Morocco.
Naima Amenzoui
Laboratory of Clinical Immunology, Inflammation and Allergy (LICIA), Casablanca Faculty of Medicine and Pharmacy, Hassan II University, Children Infectious and Clinical Immunology department Casablanca Children’s Hospital, Ibn Rochd University Hospital.Casablanca, Morocco.
Abdelhak Abkari
Pediatric Gastroenterology Unit, CHU Ibn Rochd, Faculty of Medicine, A.Harouchi Hospital CHU Ibn Rochd Casablanca, Morocco
Ahmed Aziz Bousfiha
Laboratory of Clinical Immunology, Inflammation and Allergy (LICIA), Casablanca Faculty of Medicine and Pharmacy, Hassan II University, Children Infectious and Clinical Immunology department Casablanca Children’s Hospital, Ibn Rochd University Hospital.Casablanca, Morocco.

Abstract

Introduction: Morocco has made remarkable progress in the fight against tuberculosis, but the Covid-19 pandemic has affected tuberculosis control worldwide, with notable fluctuations in tuberculosis epidemiology during and after the pandemic.


Aim: To describe the impact of the Covid-19 pandemic on the rate of hospitalization for tuberculosis and its different localizations in children.


Methods: We conducted a retrospective study based on the analysis of medical records of TB patients hospitalized within the Children’s Hospital in Casablanca, during the periods before (2018-2019), during (2020) and after (2021-2022) Covid-19 quarantine.


 


Results: Throughout the study period (2018-2022), the total number of patients hospitalized in our department was 7390, including 283 children were hospitalized for tuberculosis, with a mean age of 6 years. Before the Covid-19 pandemic, the average number of tuberculosis cases was 49 per year, of which the percentage of pulmonary tuberculosis was 32% and extra-pulmonary tuberculosis 68%. The number of cases was 23 per year during the quarantine period, with a percentage of pulmonary tuberculosis of 26% and extra-pulmonary tuberculosis of 74%. After the quarantine period, this number rose to 81 cases per year, of which 21% were pulmonary tuberculosis and 79% extrapulmonary tuberculosis (pleural tuberculosis was predominant in 44.1% of cases).


Conclusion: These results are consistent with data published by the World Health Organization, and with the findings of another study we carried out on the impact of COVID-19 on hospital admissions for acute lower respiratory tract infections. It is very likely that ...(abstract truncated at 250 words).

Keywords:

TB epidemiology , childhood TB , COVID-19 , extrapulmonary TB , TB hospitalization , Morocco

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References

  1. Janah H, Souhi H, Kouismi H. Risk Factors for Pulmonary Tuberculosis Mortality. Pan Afr Medj.2014 ;19 :347.
  2. Elfihri S, Ben Amor J, Zahraoui R. Diagnostic aspects of childhood tuberculosis: experience of the Moulay-Youssef hospital, Rabat, Morocco. Journal of Respiratory Diseases. 2017; 34: A17.
  3. Mahaman L H, Ousmane A, Oumarou A, et al. Epidemiological, clinical and evolutionary profile of tuberculosis patients at the Regional Hospital Center (CHR) of Maradi, Republic of Niger”. Pan AfrMed J. 33:120.
  4. Dylan B, Eli O, Nathavitharana R, et al. FAST Tuberculosis Transmission Control Strategy Speeds the Start of Tuberculosis Treatment at a General Hospital in Lima, Peru. The International Journal of Tuberculosis and Lung Disease. 2022;14(9):1120-6.
  5. Polidori, M. Cristina, Helmut S, et al. COVID-19 Mortality as a Fingerprint of Biological Age. Res Rev.2021; 67:101308.
  6. The Union. A century of leadership in lung health [Internet]. 2020 Available from: https://theunion.org/about-us/a-century-of-leadership-in-lung-health
  7. The Global Fund. The Impact of COVID-19 on HIV, TB and Malaria Services and Systems for Health [Internet]. 2021. Available from: https://www.theglobalfund.org/en/updates/2021/2021-04-13-the-impact-of-covid-19-on-hiv-tb-and-malaria-services-and-systems-for-health/
  8. « Impact of the COVID-19 Pandemic on TB Detection and Mortality in 2020 »;2020: https://www.who.int/publicaWorld Health Organization. Impact of the COVID-19 Pandemic on TB Detection and Mortality in 2020. 2020. Available from: https://www.who.int/publications/m/item/impact-of-the-covid-19-pandemic-on-tb-detection-and-mortality-in-2020.
  9. Migliori G, Giovanni B, Pei Min T, et al. Worldwide Effects of Coronavirus Disease Pandemic on Tuberculosis Services. Emerg Infect Dis. 2020 Nov;26(11):2709-2712.
  10. Visca D, Ong S, Tiberi R, Centis L, et al. Tuberculosis and COVID-19 Interaction: A Review of Biological, Clinical and Public Health Effects. Pneumology.2021: 151‑65.
  11. Migliori G, Giovanni B, Visca D, et al. Tuberculosis, COVID-19 and Hospital Admission: Consensus on Pros and Cons Based on a Review of the Evidence. Pneumology. 2021 Mai-Juin; 27(3):248-256.
  12. Visca D, Zampogna E, Giovanni S, et al. Pulmonary Rehabilitation Is Effective in Patients with Tuberculosis Pulmonary Sequelae. Eur Respir; 53(3): 1802184.
  13. Visca D, Zampogna E. The need for pulmonary rehabilitation after treatment for tuberculosis. Int J Tuberc Lung Dis. 2020;24(7):720-722.
  14. Visca D, Simon T, Emanuele P, Antonio S, et al. Tuberculosis in the time of COVID-19: quality of life and digital innovation. Eur Respir J. 2020;56(2):2001998.
  15. Echeverría G, Espinoza W, Waard JH. How TB and COVID-19 Compare: An Opportunity to Integrate Both Control Programmes . Int J Tuberc Lung Dis. 2020;24(9):971-974.
  16. Loveday M, Cox H, Evans D. Opportunities from a New Disease for an Old Threat: Extending COVID-19 Efforts to Address Tuberculosis in South Africa. S Afr Med J. 2020;110(12):1160-1167.
  17. Casco N, Jorge L, Palmero D, et al. TB and COVID-19 Co-Infection: Rationale and Aims of a Global Study. Int J, Tuberculosis Lung Dis. 2021;25(1):78-80.
  18. Catherine WM, Migliori G, Raviglione M et al. Epidemic and Pandemic Viral Infections: Impact on Tuberculosis and the Lung: A Consensus by the World Association for Infectious Diseases and Immunological Disorders (WAidid), Global Tuberculosis Network (GTN), and Members of the European Society of Clinical Microbiology and Infectious Diseases Study Group for Mycobacterial Infections (ESGMYC) ». Eur Respir J. 2020;56(4):2001727.
  19. Therese K, Nel Jason L, Jhanna U. Previous and Active Tuberculosis Increases Risk of Death and Prolongs Recovery in Patients with COVID-19. Infect Dis. 2020;52(12):902-907.
  20. Western Cape Department of Health in collaboration with the National Institute for Communicable Diseases, South Africa. Risk Factors for Coronavirus Disease 2019 (COVID-19) Death in a Population Cohort Study from the Western Cape Province, South Africa . Clin Infect Dis. 2020 ;73(7).
  21. McGill International TB Center. Impact of Covid-19 on tuberculosis services [Internet].2020.Availablefrom:https://www.mcgill.ca/tb/files/tb/covid_tb_briefing_fr.pdf
  22. World Health Organization. WHO Consolidated Guidelines on Tuberculosis: Module 5: Management of Tuberculosis in Children and Adolescents. 2022. Available: https://www.who.int/publications-detail-redirect/9789240046764.
  23. World Health Organization. Tuberculosis deaths increase for first time in more than a decade due to COVID-19 pandemic [Internet]. 2021. Available from: https://www.who.int/fr/news/item/14-10-2021-tuberculosis-deaths-rise-for-the-first-time-in-more-than-a-decade-due-to-the-covid-19-pandemic.
  24. Ramamon J. Extra-pulmonary tuberculosis in children hospitalized at Fianarantsoa hospital, Service de pédiatrie CHU Andrainjato Fianarantsoa. Rev. Malg. Ped. 2019;2(1):110-118.
  25. Sepulveda E, Fonseca EV, Yunda LF, et al. Extrapulmonary Tuberculosis in Colombian Children: Epidemiological and Clinical Data in a Reference Hospital . Int J Mycobacteriol. 2017;6:132-7.
  26. Balkissou A, Donkou F, Adamou D et al. Incidence and Predictors of Poor Outcome among childhood Tuberculosis in the North of Cameroon, Regional Hospital of Garoua, Cameroon. 2022; Health sci. dis ; 23(8): 15-21.
  27. Chahboune M, Barkaoui M, Iderdar Y, et al. Epidemiological profile and diagnostic and evolutionary features of TB patients at the Diagnostic Centre for Tuberculosis and Respiratory Diseases in Settat, Morocco. The Pan African Medical Journal 42 (2022): 185.
  28. Wang B, Xiangzhen G, Yuling H, et al. Epidemiological Characteristics of Common Respiratory Infectious Diseases in Children before and during the COVID-19 Epidemic. Frontiers in Pediatrics 11 (2023): 1212658.
  29. Department of Epidemiology and Disease Control. National Care Guide of Tuberculosis in Children and Adolescents. 2020. Available from: Guide PEC TB enfant et adolescent VF réctifiée 29 nov 2020.pdf.
  30. Vecchio A, Scarano S, Amato C, et al. Effects of COVID-19 pandemic on pediatric tuberculosis: decrease in notification rates and increase in clinical severity. Eur J Pediatr. 2023;182(7):3281–3285.
  31. Lakoh S, Jiba DF, Baldeh M, Adekanmbi O, Barrie U, Seisay AL, et al. Impact of COVID-19 on Tuberculosis Case Detection and Treatment Outcomes in Sierra Leone. Trop Med Infect Dis. 2021 Aug 19;6(3):154.
  32. Muniz R, Tina Le, Cuevas-Mota J, et al. Impact of Covid-19 on tuberculosis detection and treatment in Baja California, Mexico, Frontiers in Public Health. 2022 :10 :921596.
  33. D. Behera. TB control in India in the COVID era. Indian Journal of Tuberculosis, 2021.128-133.
  34. Beyene N, Sitotaw A, Tegegn B. The impact of COVID-19 on the tuberculosis control activities in Addis Ababa. Pan Afr Med J. 2021.8 :38 :243.
  35. Macintyre C. Case isolation, contact tracing, and physical distancing are pillars of COVID-19 pandemic control, not optional choices. Lancet Infect Dis. 2020;20(10):1105-1106.
  36. Yuen K, Ye Z, Fung S, et al. SARS-CoV-2 and COVID-19: The most important research questions. Cell Biosci. 2020;10:40.
  37. Hogan A, Jewell B, Sherrard-Smith E, et al. Potential impact of the COVID-19 pandemic on HIV, tuberculosis, and malaria in low-income and middle-income countries: a modelling study. Lancet Glob Health. 2020;8(9):e1132-e1141.
  38. Kruk M, Gage A, Joseph N, et al. Mortality due to low-quality health systems in the universal health coverage era: a systematic analysis of amenable deaths in 137 countries. Lancet. 2018;392(10160):2203-2212.
  39. Dye C, Williams B.The population dynamics and control of tuberculosis. Science. 2010;328(5980):856-861.
  40. Forni G, Mantovani A, Forni G, Mantovani A, Moretta . COVID-19 vaccines: where we stand and challenges ahead. Cell Death Differ. 2021;28(2):626-639.